Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep343 | Endocrine-Related Cancer | ECE2024

In silico and ex vivo identification of gonadotropin-related genes involved in ovarian cancer

Lazzaretti Clara , Melli Beatrice , Sperduti Samantha , Perri Carmela , Baschieri Lara , Ylenia Cusenza Vincenza , Martinelli Sandra , Nicoli Davide , Palicelli Andrea , Vincenzo Mandato Dario , Aguzzoli Lorenzo , Simoni Manuela , Casarini Livio

Serous ovarian cancer is one of the leading causes of death among all gynaecological malignancies. Even though a hereditary component has been suggested, most ovarian carcinomas are sporadic and markers for a diagnosis at an early stage of the disease are still to be identified. Since gonadotropins may stimulate the growth of certain cancer cells, we aim to identify tumour markers linked to gonadotropin receptor-mediated pathways. Through an in silico and ex vivo<...